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Evaluation of the effects of acyclovir and/or human amniotic membrane on herpes virus culture and qu
·AIM: To investigate the permeability of amniotic membrane in herpes virus cell culture to acyclovir with real time pol......
AIM:TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) has been reported to specifically induceapoptosis o......
The synthesis and cytotoxic activity of novel organogermanium sesquioxides with anthraquinone or nap
Four novel organogermanium sesquioxides with anthraquinone or naphthalene moiety were synthesized.The structures were ch......
DNA-based vaccination induces humoral and cellular immune responses against hepatitis B virus surfac
AIM To develop a safe and effective DNAvaccine for inducing humoral and cellularimmunological responses against hepatit......
To study the antiviral effect of Hypericum perforatum L. extract (HPE) on influenza A virus (IAV) (H1N1) in vitro and in......
Phytochemical investigation of the aerial parts of Leonurus japonicus led to the isolation of one unusual clerodane dite......
Response to Hepatocarcinoma Hca-F of Mice Immunized with Heat Shock Protein 70 from Elemene Combo Tu
To analyze immune response to murine hepatocarcinoma Hca-F of mice immunized with heat shock protein 70 (HSP70) derived ......
[Objective] To study the effects of ethanol extract of POLLEN TYPHAE(EEPT)on immune function in C57BL/6 tumor bearing mi......
Oleanolic acid isolated from ethanolic extract of Phytolacca decandra induces apoptosis in A375 skin
OBJECTIVE: Oleanolic acid(OA) has been reported to have anticancer effects, but the extent of its cytotoxicity, its abil......
Synthesis, Crystal Structures, and Binding Behaviors with CT-DNA/BSA, Antimicrobial and Cytotoxic Ac
Three new acylhydrazones containing pyrazine ring (C12H11N5O2·CH3COOH,1;C13H13N5O·2CH3COOH,2;C13H13N5O3·C13H13N5O3,3)......
研究了聚乙二醇改性碳纳米管(PEG-CNTs)对人胚肾细胞(293T)及人肝癌细胞(HepG2)的体外细胞毒性.在染毒24、48和72 h后,用水溶性四......
目的:研究内分泌干扰物双酚芴对MCF-7乳腺癌细胞的毒性效应。方法:用不同浓度(10^-5~10^-12 mol/L)的双酚芴分别暴露MCF-7细胞,通......
目的探讨水溶性蜂胶对人牙髓成纤维细胞的毒性作用,为蜂胶的临床应用提供理论依据。方法用一种新的四唑类化合物MTS比色法检测人牙......
目的:构建以BCG为栽体的rBCG-HPV16 E6-E7疫苗,研究rBCG-HPV16 E6-E7重组表达体对小鼠免疫功能的影响,初步评价此疫苗对HPV相关肿瘤(宫......
目的:对比研究4种第七代牙本质粘结剂对人牙髓成纤维细胞的毒性作用,初步探讨其生物安全性。方法:组织块培养法原代培养人牙髓成纤维......
对比研究羟丁酸钠和氯胺酮对原代培养大鼠心肌细胞的毒性作用。方法 将经原代培养成活4d后的大鼠心肌细胞分为5组,每组6孔。包括对......
目的 预测原发性肝癌高表达抗原GPC-3的HLA-A2限制性细胞毒性T淋巴细胞(CTL)表位.方法 通过国家生物技术信息中心(NCBI)数据库获取GPC-......
目的:探讨慢性乙型肝炎(CHB)患者外周血乙型肝炎病毒(HBV)特异性细胞毒性T淋巴细胞(CTLs)表面CD244与程序性死亡蛋白1(PD-1)的共表达模式及......
目的:分析弥漫大B细胞淋巴瘤(DLBCL)抗原特异T细胞受体(TCR)Vα23-Vβ13基因修饰T细胞后的体外特异性杀伤活性.方法:扩增并克隆已鉴定的D......
目的研究抗病毒治疗前后慢性丙型肝炎患者CD4^+CD25^+调节性T细胞(Treg)频率和功能的变化。方法筛选HLA—A2阳性慢性丙型肝炎患者31例,......
为了探讨新疆胀果甘草总黄酮(general flavonoids,GFs)对宫颈癌细胞的细胞毒活性,自制备胀果甘草GFs,通过离子阱喷雾式质谱技术分析,建立......
从鸦胆子(Brucea javanica)种子的甲醇提取物中分离和鉴别得到11个化合物,经波谱数据分析分别鉴定为鸦胆子内酯A(1),鸦胆子素D(2),鸦胆子苷A......
目的研究黄杨宁注射液对细菌内毒素检查试验的干扰情况,并建立其细菌内毒素检查的方法.方法参照中国药典 2000年版二部附录Ⅺ E 细......
目的制备胶质瘤光动力疫苗并检测体外抗肿瘤效应。方法采用4种不同方法制备胶质瘤疫苗。冻融疫苗:冻融法制备人胶质瘤细胞U251抗原,......
目的:研究肿瘤抗原负载的树突状细胞(DCs)对原发性肝癌肿瘤浸润淋巴细胞(TILs)体外增殖和抗瘤作用的影响.方法:将自体肿瘤细胞匀浆......
目的评价自制多西环素纳米脂质体缓释凝胶的生物相容性,及对体外培养小鼠成纤维细胞的毒性。方法选取体外培养的小鼠成纤维细胞L-9......
研究交联透明质酸体外降解特性和细胞毒性,为评价其作为医用生物材料的安全性提供依据.通过化学交联法制备交联HA,采用MTT法测定材料......
目的研究弗氏枸橼酸杆菌CF74的FliS蛋白功能。方法构建弗氏枸橼酸杆菌CF74 fliS的精确缺失突变株(CF74ΔfliS)及其互补菌株(CF74pfliS......
Therapeutic effect of intravesical or intratumoral injection of oncolysate transfected with recombin
Oncolysate, a debris of tumor cells, has been provento be effective in tumor active immunotherapy, it wasreported that t......
根管治疗中使用的消毒药物和根充材料对人体的安全性历来受到人们的关注。细胞毒性是评价其安全性的重要指标之一。下面就近年来有......
采用盐析法提取3株海水鱼类致病性弧菌的胞外产物(ECPs),并应用草鱼吻端成纤维(PSF)细胞分别对ECPs进行细胞毒性分析。结果表明,3种ECP......
目的:预测人卵巢癌相关抗原OVA66的B细胞表位。方法:B细胞表位预测,以单参数(亲水性、可及性、柔韧性、极性)预测为基础,结合ABCpred预测......
目的:观察羟基脲(Hydroxyurea,HU)对雄性大鼠Sertoli-germ细胞共培养的细胞毒性作用。方法:在Sertoli-germ细胞共培养模型中分别加入不......
目的探讨细胞毒蛋白TIA1和Granzyme B在鼻NK/T细胞淋巴瘤(NK/T)的表达及意义.方法以NK/T淋巴瘤35例石蜡组织标本为研究对象,同部位......
目的 体外实验探索骨水泥单体甲基丙烯酸甲酯(methyl methacrylate,MMA)对斯普拉格大鼠(Sprague Dawley,SD)乳鼠脊髓背根神经元的影响......
The extracts of Prunella vulgaris L. (Labiatae), a popular Western and Chinese herbal medicine, was shown to have anti-i......